Switching antidepressants pdf uk

Antidepressants, a guide to switching and withdrawing mims. Crosstapering is an option when switching between some antidepressants, and is usually preferred to abruptly stopping the first antidepressant 2. Conservative switching strategies involve gradually tapering the first antidepressant followed by an adequate. Switching and stopping antidepressants australian prescriber. Fluoxetine maois mirtazapine paroxetine reboxetine sertraline trazodone. It is considered safer, in order to avoid precipitating drug interactions, to incrementally reduce the dose of the first antidepressant and discontinue it before.

All antidepressant switches must be carried out cautiously and under close observation. Uk teratology information service uktis for pregnancy and some breastfeeding. For advice on switching treatments please refer to the psychotropic drug. Nice suggests evidence for switching from one antidepressant to another is more favourable than increasing the dose of an antidepressant. Guidelines for switching between specific antidepressants. Instructions for changing or stopping antidepressants.

Ssris less likely to cause manic switch than tcasmaois. Nottinghamshire gps guide to antidepressants prescribing, swapping and stopping. Guidelines on choice and selection of antidepressants for the. When switching between selective serotonin reuptake inhibitors, tricyclic and related antidepressants, individual patient circumstances should be considered see answer section. The tables below have been adapted from the maudsley prescribing guidelines 2,3.

Trimipramine is a tricyclic antidepressant tca indicated for the treatment of depressive. As previously, every effort was taken to make recommendations explicitly evidence based. It is unnecessary if switching from fluoxetine because of the long halflife of the drug see direct switch. Switching between tricyclic, ssri and related antidepressants. The following table is intended for general guidance only. How do you switch between tricyclic, ssri and related antidepressants. Prescribing guidelines for depression oxford health nhs. Dsmiv diagnostic and statistical manual of mental disorders.

Guidance on the use of antidepressants for the treatment of. Pdf switching and stopping antidepressants researchgate. Switching from one antidepressant to another is frequently indicated due to an inadequate treatment response or unacceptable adverse effects. Antidepressants, a guide to switching and withdrawing. Generally switching with another ssri before considering alternative class is the best course of action many patients who cannot tolerate one ssri will tolerate another. This revision of the bap guidelines for treating depressive disorders with antidepressants anderson et al.